p53 Antibodies
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63 products from 3 suppliers, 3 RRID-verified.
The most cited p53 antibody is Cell Signaling Technology 2524 with 142 RRID-verified research citations. 3 products from 2 suppliers are compared on this page. Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence (PubMed:11025664, PubMed:12524540, PubMed:12810724, PubMed:15186775, PubMed:15340061, PubMed:17317671, PubMed:17349958, PubMed:19556538, PubMed:20673990, PubMed:20959462, PubMed:22726440, PubMed:24051492, PubMed:24652652, PubMed:35618207, PubMed:36634798, PubMed:38653238, PubMed:9840937).
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Frequently Asked Questions
What is p53?
p53, also known as tumor protein p53, TP53, cellular tumor antigen p53, or transformation-related protein 53 (TRP53) is a regulatory transcription factor protein that is often mutated in human cancers. The p53 proteins are crucial in vertebrates, where they prevent cancer formation. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. Hence TP53 is classified as a tumor suppressor gene.
Source: Wikipedia
What diseases are associated with p53?
p53 has been associated with a variety of human cancers. This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expr
Source: NCBI Gene 7157
Which p53 antibody is most cited in research?
Cell Signaling Technology 7074 (Anti-rabbit IgG, HRP-linked Antibody) with 2,293 RRID-verified research citations.
Source: Antibody Registry (RRID)
What applications are p53 antibodies used for?
p53 antibodies are commonly validated for WB, IP, IHC, IF, FC, ChIP, ELISA. Application data is sourced from supplier specifications and verified through the Antibody Registry.
Source: Antibody Registry (RRID)
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